Isotopically Labeled Compounds
Medchemexpress LLC Pyridostigmine-d6 bromide | 2375858-08-3 | 100.0% | 5 MG
Pyridostigmine-d6 bromide is a deuterium-labeled Pyridostigmine, functioning as a parasympathomimetic and a reversible cholinesterase inhibitor. It is used as a tracer and an internal standard in quantitative analyses.
- Deuterium-labeled compound
- Functions as a parasympathomimetic and reversible cholinesterase inhibitor
- Used as a tracer for quantitative analysis
- Serves as an internal standard in analytical techniques like NMR, GC-MS, and LC-MS
- Incorporates stable heavy isotopes
Medchemexpress LLC Adenine-d (6-aminopurine-d1) | 109923-52-6 | 99.9% | 5 MG
Adenine-d is a deuterium-labeled adenine, a purine nucleobase essential for DNA and RNA. It plays a crucial role in biochemistry, including cellular respiration, ATP formation, and protein synthesis. This compound can be used as a tracer or as an internal standard for quantitative analysis.
- Used as a tracer
- Used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS
Medchemexpress LLC 5Z,8Z,11Z,14Z-Eicosatetraenoic-16,16,17,17,18,18,19,19,20,20,20-d11 acid | 2692624-11-4 | 98.0% | 315.53 | 50 MG
Arachidonic acid-d11 is the deuterium labeled Arachidonic acid. It is an essential fatty acid and a major constituent of biomembranes. This product is provided as a colorless to light yellow liquid solution.
- Deuterium labeled
- Essential fatty acid
- Major constituent of biomembranes
- Colorless to light yellow liquid
- Purity of 98.0%
- Store at -20°C for up to 2 years
Medchemexpress LLC 1-Bromotridecane-d4 10mg
1-Bromotridecane-d4 is the deuterium labeled 1-Bromotridecane[1]
Medchemexpress LLC N-Fmoc-leucine-d3 | 538372-74-6 | 99.3% | 356.43 | C21H20D3NO4 | 100 MG
Deuterated Fmoc-protected leucine is a stable-isotope labeled amino acid derivative used as a tracer and internal standard for quantitative analysis by NMR, GC-MS, and LC-MS. It is supplied as a white to off-white solid of high purity suitable for analytical and research applications.
- Deuterium-labeled Fmoc-protected leucine for isotope-dilution quantitation.
- Suitable as tracer and internal standard for NMR, GC-MS, and LC-MS.
- High purity (≈99.3%) for accurate analytical results.
- White to off-white solid form for easy handling and storage.
- Molecular weight 356.43 and CAS number 538372-74-6.
Medchemexpress LLC Rivaroxaban-d4 (BAY 59-7939-d4) | 1132681-38-9 | 98.7% | 439.91 | 1 MG
Rivaroxaban-d4 (BAY 59-7939-d4) is a deuterium-labeled form of Rivaroxaban, a highly potent, selective, and direct Factor Xa (FXa) inhibitor. It demonstrates significant anti-FXa potency with an IC50 of 0.7 nM and a Ki of 0.4 nM.
- Deuterium labeled compound
- Potent, selective, and direct Factor Xa (FXa) inhibitor
- Useful as a tracer or internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- For research use only
Medchemexpress LLC Dotriacontane-d66 | 62369-68-0 | 99.1% | 517.27 | 100 MG
Dotriacontane-d66 is a deuterium labeled Dotriacontane. It can be used as a tracer and as an internal standard for quantitative analysis. Deuteration has gained attention due to its potential to affect the pharmacokinetic and metabolic profiles of drugs.
- Used as a tracer and internal standard
- Suitable for quantitative analysis by NMR, GC-MS, or LC-MS
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs
Medchemexpress LLC Sphingosine-1-phosphate (S1P) | 26993-30-6 | 99.5% | 379.47 | 25 MG
Sphingosine-1-phosphate (S1P) is an agonist of S1P1-5 receptors and a ligand of GPR3, GPR6 and GPR12. It functions as an intracellular second messenger and mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors. This lipid mediator stimulates DNA synthesis, cell proliferation, and migration.
- Agonist of S1P1-5 receptors and a ligand of GPR3, GPR6, and GPR12.
- Functions as an intracellular second messenger.
- Mobilizes Ca2+ as an extracellular ligand for G protein-coupled receptors.
- Important lipid mediator.
- Stimulates DNA synthesis, cell proliferation, and migration.
- For research use only.
Medchemexpress LLC Oxprenolol-d7 hydrochloride | 1189649-47-5 | 98.25% | 5 MG
Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride (Ba 39089) is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
- This compound can be used as a tracer.
- This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Medchemexpress LLC Oxprenolol-d7 hydrochloride | 1189649-47-5 | 98.3% | 1 MG
Oxprenolol-d7 (hydrochloride) is the deuterium labeled Oxprenolol hydrochloride. Oxprenolol hydrochloride is an orally bioavailable β-adrenergic receptor (β-AR) antagonist with a Ki of 7.10 nM in a radioligand binding assay using rat heart muscle.
- Can be used as a tracer.
- Serves as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
- Incorporates stable heavy isotopes as tracers for quantitation during drug development.
- Deuteration may affect pharmacokinetic and metabolic profiles of drugs.
Cambridge Isotope Laboratories RESVERATROL (4-HYDROXYPHENYL-13C6, 99%), 5 MG, 1185247-70-4
RESVERATROL (4-HYDROXYPHENYL-13C6, 99%), 5 MG, 1185247-70-4
Cayman Chemical Palmitoyl Ethanolamide-d4, Purity: ≥99% deuterated forms (d1-d4), CAS: 946524-34-1, 1 mg
An internal standard for the quantification of palmitoyl ethanolamide by GC- or LC-MS
Medchemexpress LLC Thiocolchicine-d3 1mg | 1314417-95-2 | 418.52 | C22H22D3NO5S | 1 MG
Thiocolchicine-d3 is a deuterium-labeled derivative of thiocolchicine used for research applications. It inhibits tubulin polymerization (reported IC50 = 2.5 μM; Ki = 0.7 μM), induces apoptosis, and can be used as a tracer or internal standard for quantitative NMR, GC-MS, or LC-MS.
- Deuterium-labeled tracer/internal standard for analytical quantitation.
- Tubulin polymerization inhibitor with reported IC50 = 2.5 μM.
- Reported Ki for tubulin binding of 0.7 μM.
- High purity (≥99.0%).
- Small pack sizes suitable for analytical applications.
- Store protected from light; stable at -80°C in solvent for up to 6 months.
Medchemexpress LLC Nortriptyline hydrochloride | 894-71-3 | 99.98% | 1 ML
Nortriptyline hydrochloride (Desmethylamitriptyline) is the main active metabolite of Amitriptyline, functioning as a tricyclic antidepressant. It also acts as a potent autophagy inhibitor and demonstrates anticancer effects.
- Potent autophagy inhibitor
- Anticancer effects
- Inhibits Norepinephrine transporter (NET, SLC6A2)
- Blocks Norepinephrine reuptake more potently than Serotonin
- Reduces viability and induces apoptosis in bladder cancer cells
- Inhibits bladder tumor growth in vivo
Medchemexpress LLC Betaine-d9 chloride | 285979-85-3 | 99.7% | 162.66 g·mol⁻¹ | C5H3D9ClNO2 | 10 MG
Betaine-d9 chloride is the deuterium-labeled analogue of betaine chloride used as a stable isotope research standard for quantitative mass spectrometry and tracer studies.
- Suitable as an internal standard for mass spectrometry.
- Deuterium-labeled tracer for isotope-labeling experiments.
- High chemical and isotopic purity for accurate quantitation.
- Supplied as a solid chloride salt for analytical workflows.
- Available in small mg-scale pack sizes for research use.